P0306 Code: 2022 Acura MDX – What It Means & Cost to Fix

P0306 Code on 2022 Acura MDX: Cylinder 6 Misfire Diagnosis for the V6

A P0306 diagnostic code on your 2022 Acura MDX indicates a cylinder 6 misfire condition. The 2022 MDX is powered by a 3.5L V6 engine producing 290 horsepower (Type S uses a 3.0L turbo V6 with 355 hp), making this code valid for all MDX V6 variants.

2022 MDX Engine Options

  • Standard MDX: 3.5L naturally aspirated V6 (290 hp)
  • MDX Type S: 3.0L twin-turbo V6 (355 hp)

Both engines have 6 cylinders, so P0306 is a valid code for any 2022 MDX.

Common Causes of P0306

  • Ignition Coil Failure: Individual coil-on-plug failures are common
  • Worn Spark Plugs: Iridium or platinum plugs degrade over time
  • Fuel Injector Issues: Clogged or malfunctioning injector
  • Carbon Buildup: Direct injection engines can accumulate valve deposits
  • Vacuum Leaks: Intake manifold or gasket leaks near cylinder 6
  • Mechanical Problems: Low compression from valve or piston issues

Acura MDX V6 Layout

The MDX's transversely-mounted V6 positions cylinder 6 at the rear of the front (firewall-side) bank. This location makes access more challenging, often requiring removal of the intake manifold cover and other components.

Parts & Tools for This Case

Based on our investigation, these parts may be needed for this repair.

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