The 2020 Nissan Maxima features the legendary 3.5L VQ35DE V6 producing 300 horsepower, paired with a CVT transmission. When P0306: Cylinder 6 Misfire Detected appears, your Maxima has identified combustion problems specifically in cylinder 6 of Nissan's flagship sedan.
Maxima VQ35 Engine
The Maxima uses the naturally aspirated VQ35DE—a proven engine found across numerous Nissan and Infiniti models. Cylinder 6 sits on one bank of the 60-degree V6. Unlike direct injection variants, the VQ35DE uses port injection, which helps keep intake valves clean.
Common P0306 Causes
Ignition coil degradation from heat cycling affects cylinder-specific spark. Spark plugs approaching service intervals produce weak ignition. Port injection keeps valves cleaner than direct injection, but fuel injector issues can still occur. Vacuum leaks create lean conditions. The Maxima's performance-oriented tuning demands proper ignition timing.
Diagnostic Procedure
Scan for all codes to understand the diagnostic picture. Access cylinder 6 and inspect ignition components. Remove and evaluate spark plug condition against mileage. Test fuel injector operation. Perform compression testing to verify mechanical health.
Four-Door Sports Car
Nissan markets the Maxima as a "4-Door Sports Car." Maintaining its V6 performance requires quality parts and timely service.