The 2022 Lexus RX represents the final year of the fourth generation, featuring the 3.5-liter V6 engine in RX 350 models producing 295 horsepower. This naturally aspirated V6 includes cylinder 5 as a legitimate position. A P0305 diagnostic trouble code indicates the engine management system has detected a misfire at this cylinder.
Understanding P0305 on Lexus V6
The P0305 code signifies "Cylinder 5 Misfire Detected." On Toyota/Lexus 3.5L V6 engines (2GR-FKS), cylinder numbering places cylinders 1-3 on the right bank and 4-6 on the left (driver's side). Cylinder 5 is the middle cylinder on the driver's side bank.
Common Causes of Cylinder 5 Misfire
The 2GR-FKS engine in the 2022 RX uses both port and direct injection (D-4S). This dual-injection system helps prevent carbon buildup. Cylinder 5 misfires typically result from ignition coil failure, spark plug wear, fuel injector issues, or mechanical problems.
Lexus Reliability Expectations
Lexus vehicles have outstanding reliability records, but components still wear over time. At the 2022 model year, typical maintenance items like spark plugs may be approaching service intervals if the vehicle has accumulated significant mileage.
Diagnostic Approach
Toyota/Lexus Techstream diagnostic equipment provides the most detailed analysis. Generic scanners can identify the code, but model-specific data aids diagnosis.