The 2022 Lexus ES 350 luxury sedan features the 3.5-liter V6 engine producing 302 horsepower. This naturally aspirated V6 includes cylinder 5 as a legitimate position. A P0305 diagnostic trouble code indicates the engine management system has detected a misfire at this cylinder.
Understanding P0305 on ES V6
The P0305 code signifies "Cylinder 5 Misfire Detected." On Toyota/Lexus 3.5L V6 engines, cylinder 5 is positioned on the driver's side (left bank) as the middle cylinder. The 2GR-FKS engine uses a transverse mounting orientation in the ES.
Dual Injection System
The ES 350's 2GR-FKS engine features Toyota's D-4S dual injection system combining port and direct injection. This technology helps prevent carbon buildup on intake valves while providing the benefits of direct injection for power and efficiency.
Common Misfire Causes
Cylinder 5 misfires on the ES 350 typically result from ignition coil degradation, spark plug wear approaching service interval, fuel injector malfunction (either port or direct injector), or mechanical issues affecting cylinder 5 compression or valve sealing.
Lexus Service Excellence
Lexus owners expect premium service. Diagnosis at Lexus dealers ensures access to Techstream diagnostics and factory-trained technicians familiar with the 3.5L V6's specific characteristics.