The P0303 diagnostic trouble code on your 2022 Lexus IS indicates the powertrain control module has detected consistent misfires in cylinder 3. The refreshed 2022 IS continues with proven turbo and V6 powertrains.
2022 IS Powertrain Options
The 2022 IS 300 offers a 2.0L turbocharged four-cylinder (RWD) or 3.5L V6 (AWD). The IS 350 uses the 3.5L V6 with optional AWD. The IS 500 adds a 5.0L V8. Cylinder 3 location varies by engine configuration.
Typical Causes
- Ignition Coil Problems: High-performance applications stress coils
- Spark Plug Condition: Sport driving accelerates wear
- Boost System Leaks: Turbo IS 300 sensitive to intake leaks
- Fuel Injector Issues: Direct injection deposits or failures
- Carbon Accumulation: GDI engines develop valve deposits
Diagnostic Process
Identify your engine configuration first. Use Lexus diagnostic equipment for full data access. Monitor appropriate parameters for your engine type. Test ignition components systematically.
Repair Recommendations
Replace faulty ignition coils with Denso OEM parts. Install engine-appropriate spark plugs. Repair boost leaks on turbo models. Professional carbon cleaning addresses valve deposits on higher mileage vehicles.