The P0303 diagnostic trouble code on your 2022 Infiniti QX60 indicates the engine control module has detected consistent misfires in cylinder 3. The completely redesigned 2022 QX60 features the VQ35DD 3.5L V6 engine.
3.5L V6 Engine Layout
The 2022 QX60 uses the VQ35DD 3.5L V6 producing 295 horsepower with direct fuel injection. Cylinder 3 is located on the front bank of this V6. This proven Nissan V6 architecture has been refined for the new QX60.
Common Causes
- Ignition Coil Failure: Individual coil-on-plug units can fail
- Spark Plug Wear: Iridium plugs eventually need replacement
- Fuel Injector Problems: Direct injection deposits
- Carbon Buildup: GDI technology leads to valve deposits
- Intake Manifold Leaks: Gasket or vacuum line failures
Diagnostic Approach
Use a Nissan/Infiniti compatible scanner for detailed diagnostics. Monitor misfire counts and fuel trim data. Test ignition components through swap testing. The VQ35 has a proven diagnostic record.
Repair Solutions
Replace failed ignition coils with OEM or quality aftermarket parts. Install Infiniti-specified iridium spark plugs. Clean or replace fuel injectors as needed. Consider carbon cleaning for higher mileage vehicles.