A P0303 diagnostic code on your 2022 Dodge Durango indicates the powertrain control module has detected repeated misfires in cylinder 3. The 2022 Durango offers proven V6 and V8 powertrains with specific diagnostic considerations.
Engine Configuration
The 2022 Durango offers the 3.6L Pentastar V6, 5.7L HEMI V8, or 6.4L HEMI V8 (SRT and R/T models). Cylinder 3 is on the driver's side for all engines. The 5.7L includes MDS cylinder deactivation; the 6.4L does not.
Typical Causes
- Ignition Coil Degradation: Coil-on-plug failures from heat and use
- Spark Plug Issues: HEMI two-piece plugs require proper service
- MDS Component Failure: 5.7L HEMI lifters and solenoids
- Fuel Delivery Problems: Injector deposits or failures
- Vacuum Leaks: Intake manifold or gasket issues
Diagnostic Process
Use a diagnostic scanner to access engine-specific data. For 5.7L models, monitor MDS status and misfire patterns. Test ignition components through swap testing. Check fuel delivery and intake system integrity.
Repair Recommendations
Replace failed ignition coils with Mopar parts. Use proper HEMI spark plug service techniques. For MDS-related issues on 5.7L engines, lifter replacement may be required. The 6.4L lacks MDS, simplifying its diagnosis.